| Date | Location | Result | |
| 3/9/06 | Quicken Loans Arena, Cleveland, Ohio | Kent State 76, Buffalo 67 | Box score |
| 03/06/06 | Alumni Arena (Buffalo, NY) | Buffalo 80, Ball State 72 | Box score |
| 03/04/06 | Millett Hall, Oxford, Ohio | Miami 74, Buffalo 65 | Box score |
| 03/01/06 | Alumni Arena (Buffalo, NY) | Buffalo 83, Akron 71 | Box score |
| 02/26/06 | Alumni Arena (Buffalo, NY) | Buffalo 81, Bowling Green 67 | Box score |
| 02/22/06 | Convocation Center - Athens, Ohio | Ohio 85, Buffalo 72 | Box score |
| 02/18/06 | New Rochelle, NY - Hynes Center | Iona College 93, Buffalo 75 | Box score |
| 02/15/06 | Alumni Arena (Buffalo, NY) | Kent State 111, Buffalo 107 | Box score |
| 02/11/06 | Mount Pleasant, Mich. (Rose Arena) | Buffalo 73, Central Michigan 59 | Box score |
| 02/07/06 | Worthen Arena - Muncie, Ind. | BALL STATE 67, Buffalo 60 | Box score |
| 02/04/06 | Alumni Arena (Buffalo, NY) | Miami 81, Buffalo 74 | Box score |
| 02/01/06 | Akron, Ohio (Rhodes Arena) | Akron 75, Buffalo 61 | Box score |
| 01/29/06 | Kent, Ohio (M.A.C. Center) | Kent State 70, Buffalo 52 | Box score |
| 01/26/06 | Alumni Arena (Buffalo, NY) | Buffalo 70, Ohio 51 | Box score |
| 01/24/06 | Bowling Green, Ohio (Anderson Arena) | Buffalo 76, Bowling Green 73 | Box score |
| 01/21/06 | Alumni Arena (Buffalo, NY) | Central Michigan 71, Buffalo 61 | Box score |
| 01/18/06 | Alumni Arena (Buffalo, NY) | Buffalo 75, Ball State 64 | Box score |
| 01/14/06 | Alumni Arena (Buffalo, NY) | Buffalo 73, Western Michigan 62 | Box score |
| 01/10/06 | John F. Savage Hall (Toledo, OH) | Toledo 73, Buffalo 70 | Box score |
| 01/07/06 | NIU Convocation Center | Northern Illinois 84, Buffalo Bulls 82 | Box score |
| 01/04/06 | Alumni Arena (Buffalo, NY) | Buffalo 78, Eastern Michigan 62 | Box score |
| 12/30/05 | Memorial Hall-Dover,Del. | Univ. of Buffalo 56, Delaware State 51 | Box score |
| 12/21/05 | Alumni Arena (Buffalo, NY) | Buffalo 68, Elon 67 | Box score |
| 12/10/05 | Alumni Arena (Buffalo, NY) | Buffalo 62, Rutgers 53 | Box score |
| 12/06/05 | Lynchburg, Va. (Vines Center) | Buffalo 66, Liberty 53 | Box score |
| 12/03/05 | Niagara Un., N.Y. Gallagher Center | Buffalo 68, Niagara 59 | Box score |
| 11/30/05 | Alumni Arena (Buffalo, NY) | Buffalo 85, Fresno State 69 | Box score |
| 11/26/05 | Las Vegas, NV Valley High School | Buffalo 66, Detroit 60 | Box score |
| 11/25/05 | Las Vegas, Nevada - Valley High School | Buffalo 71, Jackson State 65 | Box score |
| 11/22/05 | Silvio O. Conte Forum, Chestnut Hill, MA | BOSTON COLLEGE 92, BUFFALO 63 | Box score |
| 11/20/05 | Alumni Arena (Buffalo, NY) | Buffalo 96, Buffalo State 61 | Box score |
| 11/18/05 | Alumni Arena (Buffalo, NY) | Buffalo 81, Canisius 76 | Box score |